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Nature 494 , 375379 (2013)

10.1016/0165-4608(92)90336-7 Cancer Genet Cytogenet

PT-141 injection is usually administered subcutaneously about 45 minutes to 1 hour before sexual activity

Collectively, these findings indicate that non-selective or excessive chelation of brain iron may disrupt physiological metallostasis, emphasizing the need for precisely titrated, brain-targeted anti-ferroptotic interventions with balanced efficacytoxicity profiles. Beyond traditional chelators, several natural compounds have also shown potential in regulating iron transport proteins

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